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TitleEstrogen receptor ligands: design and synthesis of new 2-arylindene-1-ones
Journal, issue, pagesBioorg. Med. Chem. Lett., Vol. 15, Page 3137-3142, Year 2005
Publish dateApr 6, 2005 (structure data deposition date)
AuthorsMcDevitt, R.E. / Malamas, M.S. / Manas, E.S. / Unwalla, R.J. / Xu, Z.B. / Miller, C.P. / Harris, H.A.
External linksBioorg. Med. Chem. Lett. / PubMed:15876535
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-1zaf:
Crystal structure of estrogen receptor beta complexed with 3-Bromo-6-hydroxy-2-(4-hydroxy-phenyl)-inden-1-one
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-789:
3-BROMO-6-HYDROXY-2-(4-HYDROXYPHENYL)-1H-INDEN-1-ONE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION/TRANSFERASE / estrogen receptor / estrogen receptor beta / er-beta / er / estrogen / nuclear receptor / transcription factor / agonist / TRANSCRIPTION-TRANSFERASE COMPLEX

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