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TitleStructure and inhibition of the human cell cycle checkpoint kinase, Wee1A kinase: an atypical tyrosine kinase with a key role in CDK1 regulation
Journal, issue, pagesStructure, Vol. 13, Page 541-550, Year 2005
Publish dateAug 17, 2004 (structure data deposition date)
AuthorsSquire, C.J. / Dickson, J.M. / Ivanovic, I. / Baker, E.N.
External linksStructure / PubMed:15837193
MethodsX-ray diffraction
Resolution1.81 Å
Structure data

PDB-1x8b:
Structure of human Wee1A kinase: kinase domain complexed with inhibitor PD0407824
Method: X-RAY DIFFRACTION / Resolution: 1.81 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-824:
9-HYDROXY-4-PHENYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / kinase / cell cycle / wee1

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