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TitleSolution Structural Study of a DNA Duplex Containing the Guanine-N7 Adduct Formed by a Cytotoxic Platinum-Acridine Hybrid Agent
Journal, issue, pagesBiochemistry, Vol. 44, Page 6059-6070, Year 2005
Publish dateOct 16, 2004 (structure data deposition date)
AuthorsBaruah, H. / Wright, M.W. / Bierbach, U.
External linksBiochemistry / PubMed:15835895
MethodsNMR (solution)
Structure data

PDB-1xrw:
Solution Structure of a Platinum-Acridine Modified Octamer
Method: SOLUTION NMR

Chemicals

ChemComp-2PT:
1-[2-(ACRIDIN-9-YLAMINO)ETHYL]-1,3-DIMETHYLTHIOUREA-PLATINUM(II)-ETHANE-1,2-DIAMINE

KeywordsDNA / platinum / acridine / dual binding mode / major groove / unwinding

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