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TitleAspirin induces its anti-inflammatory effects through its specific binding to phospholipase A2: crystal structure of the complex formed between phospholipase A2 and aspirin at 1.9 angstroms resolution.
Journal, issue, pagesJ. Drug Target., Vol. 13, Page 113-119, Year 2005
Publish dateApr 3, 2003 (structure data deposition date)
AuthorsSingh, R.K. / Ethayathulla, A.S. / Jabeen, T. / Sharma, S. / Kaur, P. / Singh, T.P.
External linksJ. Drug Target. / PubMed:15823962
MethodsX-ray diffraction
Resolution1.93 Å
Structure data

PDB-1oxr:
Aspirin induces its Anti-inflammatory effects through its specific binding to Phospholipase A2: Crystal structure of the complex formed between Phospholipase A2 and Aspirin at 1.9A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

Chemicals

ChemComp-AIN:
2-(ACETYLOXY)BENZOIC ACID / antiinflammatory*YM

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • naja sagittifera (cobra)
KeywordsHYDROLASE / O-acetyl-oxy Phenol / complex / PLA2 / Naja Naja Sagittifera

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