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-Structure paper
Title | Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP |
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Journal, issue, pages | BIOORG. MED. CHEM. LETT., Vol. 15, Page 2041-2045, Year 2005 |
Publish date | Feb 4, 2005 (structure data deposition date) |
![]() | Cox, C.D. / Breslin, M.J. / Mariano, B.J. / Coleman, P.J. / Buser, C.A. / Walsh, E.S. / Hamilton, K. / Huber, H.E. / Kohl, N.E. / Torrent, M. ...Cox, C.D. / Breslin, M.J. / Mariano, B.J. / Coleman, P.J. / Buser, C.A. / Walsh, E.S. / Hamilton, K. / Huber, H.E. / Kohl, N.E. / Torrent, M. / Yan, Y. / Kuo, L.C. / Hartman, G.D. |
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Methods | X-ray diffraction |
Resolution | 2.5 Å |
Structure data | ![]() PDB-1yrs: |
Chemicals | ![]() ChemComp-MG: ![]() ChemComp-ADP: ![]() ChemComp-L47: ![]() ChemComp-HOH: |
Source |
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![]() | CELL CYCLE |