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TitlePurified Argonaute2 and an siRNA form recombinant human RISC.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 12, Page 340-349, Year 2005
Publish dateMar 7, 2005 (structure data deposition date)
AuthorsRivas, F.V. / Tolia, N.H. / Song, J.J. / Aragon, J.P. / Liu, J. / Hannon, G.J. / Joshua-Tor, L.
External linksNat. Struct. Mol. Biol. / PubMed:15800637
MethodsX-ray diffraction
Resolution2.5 - 2.7 Å
Structure data

PDB-1z25:
Structure of P.furiosus Argonaute with bound Mn2+
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-1z26:
Structure of Pyrococcus furiosus Argonaute with bound tungstate
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-WO4:
TUNGSTATE(VI)ION

Source
  • pyrococcus furiosus (archaea)
KeywordsGENE REGULATION / Argonaute / PIWI / active site / RNaseH / Mg2+ / RNAi / tungstate

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