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Structure paper

TitleKinetic stabilization of the native state by protein engineering: implications for inhibition of transthyretin amyloidogenesis.
Journal, issue, pagesJ. Mol. Biol., Vol. 347, Page 841-854, Year 2005
Publish dateSep 2, 2003 (structure data deposition date)
AuthorsFoss, T.R. / Kelker, M.S. / Wiseman, R.L. / Wilson, I.A. / Kelly, J.W.
External linksJ. Mol. Biol. / PubMed:15769474
MethodsX-ray diffraction
Resolution1.36 Å
Structure data

PDB-1qwh:
a covalent dimer of transthyretin that affects the amyloid pathway
Method: X-RAY DIFFRACTION / Resolution: 1.36 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHORMONE/GROWTH FACTOR / thyroid hormone / liver / plasma / cerebrospinal fluid / polyneuropathy / disease mutation / transport / thyroxine / binding protein / HORMONE-GROWTH FACTOR COMPLEX

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