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Structure paper

TitleHigh Resolution Crystal Structures of Human Cytosolic Thiolase (CT): A Comparison of the Active Sites of Human CT, Bacterial Thiolase, and Bacterial KAS I
Journal, issue, pagesJ. Mol. Biol., Vol. 347, Page 189-201, Year 2005
Publish dateJun 20, 2004 (structure data deposition date)
AuthorsKursula, P. / Sikkila, H. / Fukao, T. / Kondo, N. / Wierenga, R.K.
External linksJ. Mol. Biol. / PubMed:15733928
MethodsX-ray diffraction
Resolution1.55 - 2.26 Å
Structure data

PDB-1wl4:
Human cytosolic acetoacetyl-CoA thiolase complexed with CoA
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-1wl5:
Human cytosolic acetoacetyl-CoA thiolase
Method: X-RAY DIFFRACTION / Resolution: 2.26 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-COA:
COENZYME A

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / thiolase fold

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