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Structure paper

TitleMolecular Mechanism of Lipopeptide Presentation by CD1a.
Journal, issue, pagesImmunity, Vol. 22, Page 209-219, Year 2005
Publish dateNov 11, 2004 (structure data deposition date)
AuthorsZajonc, D.M. / Crispin, M.D. / Bowden, T.A. / Young, D.C. / Cheng, T.Y. / Hu, J. / Costello, C.E. / Rudd, P.M. / Dwek, R.A. / Miller, M.J. ...Zajonc, D.M. / Crispin, M.D. / Bowden, T.A. / Young, D.C. / Cheng, T.Y. / Hu, J. / Costello, C.E. / Rudd, P.M. / Dwek, R.A. / Miller, M.J. / Brenner, M.B. / Moody, D.B. / Wilson, I.A.
External linksImmunity / PubMed:15723809
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-1xz0:
Crystal structure of CD1a in complex with a synthetic mycobactin lipopeptide
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-JH0:
6-(HYDROXY-HEXADECANOYL-AMINO)-2-{[(4S)-2-(2-HYDROXY-PHENYL)-4,5-DIHYDRO-OXAZOLE-4-CARBONYL]-AMINO}-HEXANOIC ACID 2-[(3S)-1-(TERT-BUTYL-DIPHENYL-SILANYLOXY)-2-OXO-AZEPAN-3-YLCARBAMOYL]-(1S)-1-METHYL-ETHYL ESTER

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / beta sheet platform / MHC-fold / Protein-lipopeptide complex

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