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TitleBroadly Neutralizing Anti-HIV Antibody 4E10 Recognizes a Helical Conformation of a Highly Conserved Fusion-Associated Motif in gp41
Journal, issue, pagesImmunity, Vol. 22, Page 163-173, Year 2005
Publish dateJul 9, 2004 (structure data deposition date)
AuthorsCardoso, R.M.F. / Zwick, M.B. / Stanfield, R.L. / Kunert, R. / Binley, J.M. / Katinger, H. / Burton, D.R. / Wilson, I.A.
External linksImmunity / PubMed:15723805
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-1tzg:
Crystal structure of HIV-1 neutralizing human Fab 4E10 in complex with a 13-residue peptide containing the 4E10 epitope on gp41
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / antibody-epitope complex

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