+Search query
-Structure paper
Title | Crystal structures of 2-methylisocitrate lyase in complex with product and with isocitrate inhibitor provide insight into lyase substrate specificity, catalysis and evolution. |
---|---|
Journal, issue, pages | Biochemistry, Vol. 44, Page 2949-2962, Year 2005 |
Publish date | Mar 8, 2003 (structure data deposition date) |
Authors | Liu, S. / Lu, Z. / Han, Y. / Melamud, E. / Dunaway-Mariano, D. / Herzberg, O. |
External links | Biochemistry / PubMed:15723538 |
Methods | X-ray diffraction |
Resolution | 1.6 - 1.93 Å |
Structure data | PDB-1oqf: PDB-1xg3: PDB-1xg4: |
Chemicals | ChemComp-HOH: ChemComp-MG: ChemComp-PYR: ChemComp-SIN: ChemComp-ICT: |
Source |
|
Keywords | LYASE / structural genomics / alpha-beta barrel / swapped helix across a dimer / Structure 2 Function Project / S2F / 2-methylisocitrate lyase-product complex / succinate / pyruvate / isocitrate lyase superfamily / 2-methylisocitrate lyase-inhibitor complex / isocitrate |