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TitleCrystal structure of a substrate complex of Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FabH) with lauroyl-coenzyme A.
Journal, issue, pagesJ. Mol. Biol., Vol. 346, Page 1313-1321, Year 2005
Publish dateJul 29, 2004 (structure data deposition date)
AuthorsMusayev, F. / Sachdeva, S. / Scarsdale, J.N. / Reynolds, K.A. / Wright, H.T.
External linksJ. Mol. Biol. / PubMed:15713483
MethodsX-ray diffraction
Resolution1.85 - 2.3 Å
Structure data

PDB-1u6e:
1.85 Angstrom Crystal Structure of the C112A Mutant of Mycobacterium Tuberculosis Beta-Ketoacyl-Acyl Carrier Protein Synthase III (FabH)
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-1u6s:
Crystal Structure of the Complex Between Mycobacterium Tuberculosis Beta-Ketoacyl-Acyl Carrier Protein Synthase III and Lauroyl Coenzyme A
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-DCC:
DODECYL-COA

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsTRANSFERASE / 3-oxoacyl-[acyl-carrier-protein] synthase III / fatty acid biosynthesis / mycobacterium tuberculosis / substrate complex

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