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Structure paper

TitleBenzodipyrazoles: A New Class of Potent Cdk2 Inhibitors
Journal, issue, pagesBioorg. Med. Chem. Lett., Vol. 15, Page 1315-, Year 2005
Publish dateFeb 23, 2005 (structure data deposition date)
AuthorsDalessio, R. / Bargiottia, A. / Metz, S. / Brasca, M.G. / Cameron, A. / Ermoli, A. / Marsiglio, A. / Polucci, P. / Roletto, F. / Tibolla, M. ...Dalessio, R. / Bargiottia, A. / Metz, S. / Brasca, M.G. / Cameron, A. / Ermoli, A. / Marsiglio, A. / Polucci, P. / Roletto, F. / Tibolla, M. / Vazquez, M.L. / Vulpetti, A. / Pevarello, P.
External linksBioorg. Med. Chem. Lett. / PubMed:15713378
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-2bkz:
STRUCTURE OF CDK2-CYCLIN A WITH PHA-404611
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-SBC:
1-[4-(AMINOSULFONYL)PHENYL]-1,6-DIHYDROPYRAZOLO[3,4-E]INDAZOLE-3-CARBOXAMIDE

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / TRANSFERASE-COMPLEX / PROTEIN KINASE / SERINE/THREONINE-PROTEIN KINASE / PHOSPHORYLATION / CELL DIVISION / CYCLIN / ATP-BINDING / CELL CYCLE / MITOSIS / POLYMORPHISM

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