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TitleEffects of P47Phox C-Terminus Phosphorylation on Binding Interactions with P40Phox and P67Phox: Structural and Functional Comparison of P40Phox P67Phox SH3 Domains
Journal, issue, pagesJ. Biol. Chem., Vol. 280, Page 13752-13761, Year 2005
Publish dateAug 24, 2004 (structure data deposition date)
AuthorsMassenet, C. / Chenavas, S. / Cohen-Addad, C. / Dagher, M.-C. / Brandolin, G. / Pebay-Peyroula, E. / Fieschi, F.
External linksJ. Biol. Chem. / PubMed:15657040
MethodsX-ray diffraction
Resolution1.46 - 2 Å
Structure data

PDB-1w6x:
SH3 domain of p40phox, component of the NADPH oxidase
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1w70:
SH3 domain of p40phox complexed with C-terminal polyProline region of p47phox
Method: X-RAY DIFFRACTION / Resolution: 1.46 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-TFA:
trifluoroacetic acid

Source
  • homo sapiens (human)
KeywordsSH3 DOMAIN / NADPH OXIDASE / P40PHOX / PHAGOCYTE / P47PHOX / POLYPROLINE

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