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TitleBinding of beta-d-glucopyranosyl bismethoxyphosphoramidate to glycogen phosphorylase b: kinetic and crystallographic studies
Journal, issue, pagesBioorg. Med. Chem., Vol. 13, Page 765-772, Year 2005
Publish dateSep 1, 2004 (structure data deposition date)
AuthorsChrysina, E.D. / Kosmopoulou, M.N. / Kardakaris, R. / Bischler, N. / Leonidas, D.D. / Kannan, T. / Loganathan, D. / Oikonomakos, N.G.
External linksBioorg. Med. Chem. / PubMed:15653344
MethodsX-ray diffraction
Resolution1.83 Å
Structure data

PDB-1xc7:
Binding of beta-D-glucopyranosyl bismethoxyphosphoramidate to glycogen phosphorylase b: Kinetic and crystallographic studies
Method: X-RAY DIFFRACTION / Resolution: 1.83 Å

Chemicals

ChemComp-GL6:
N-(dimethoxyphosphoryl)-beta-D-glucopyranosylamine

ChemComp-SO4:
SULFATE ION

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-HOH:
WATER

Source
  • oryctolagus cuniculus (rabbit)
KeywordsTRANSFERASE / glycogenolysis / type 2 diabetes

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