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TitleThe Identification of Isoprenoids that Bind in the Intersubunit Cavity of Escherichia Coli 2C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Synthase by Complementary Biophysical Methods
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 61, Page 45-, Year 2005
Publish dateFeb 24, 2003 (structure data deposition date)
AuthorsKemp, L.E. / Alphey, M.S. / Bond, C.S. / Ferguson, M. / Hecht, S. / Bacher, A. / Eisenreich, W. / Rohdich, F. / Hunter, W.N.
External linksActa Crystallogr. ,Sect. D / PubMed:15608374
MethodsX-ray diffraction
Resolution1.99 - 2.3 Å
Structure data

PDB-1h47:
Structures of MECP synthase in complex with (i) CMP and (ii) CMP and product
Method: X-RAY DIFFRACTION / Resolution: 1.99 Å

PDB-1h48:
The structure of 2C-Methyl-D-erythritol 2,4-cyclodiphosphate synthase in complex with CMP and product
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-GPP:
GERANYL DIPHOSPHATE

ChemComp-ZN:
Unknown entry

ChemComp-C5P:
CYTIDINE-5'-MONOPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-CDI:
2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE

ChemComp-MN:
Unknown entry

Source
  • escherichia coli (E. coli)
KeywordsSYNTHASE / ISOPRENOID / LYASE / ISOPRENE BIOSYNTHESIS

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