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Structure paper

TitleNaphthamidine urokinase plasminogen activator inhibitors with improved pharmacokinetic properties.
Journal, issue, pagesBioorg. Med. Chem. Lett., Vol. 15, Page 93-98, Year 2005
Publish dateJul 30, 2004 (structure data deposition date)
AuthorsBruncko, M. / McClellan, W.J. / Wendt, M.D. / Sauer, D.R. / Geyer, A. / Dalton, C.R. / Kaminski, M.A. / Weitzberg, M. / Gong, J. / Dellaria, J.F. ...Bruncko, M. / McClellan, W.J. / Wendt, M.D. / Sauer, D.R. / Geyer, A. / Dalton, C.R. / Kaminski, M.A. / Weitzberg, M. / Gong, J. / Dellaria, J.F. / Mantei, R. / Zhao, X. / Nienaber, V.L. / Stewart, K. / Klinghofer, V. / Bouska, J. / Rockway, T.W. / Giranda, V.L.
External linksBioorg. Med. Chem. Lett. / PubMed:15582418
MethodsX-ray diffraction
Resolution2.02 Å
Structure data

PDB-1u6q:
Substituted 2-Naphthamadine inhibitors of Urokinase
Method: X-RAY DIFFRACTION / Resolution: 2.02 Å

Chemicals

ChemComp-745:
TRANS-6-(2-PHENYLCYCLOPROPYL)-NAPHTHALENE-2-CARBOXAMIDINE

Source
  • homo sapiens (human)
KeywordsHYDROLASE

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