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TitleStructure of a High Fidelity DNA Polymerase Bound to a Benzo[a]pyrene Adduct That Blocks Replication
Journal, issue, pagesJ. Biol. Chem., Vol. 280, Page 3764-3770, Year 2005
Publish dateSep 1, 2004 (structure data deposition date)
AuthorsHsu, G.W. / Huang, X. / Luneva, N.P. / Geacintov, N.E. / Beese, L.S.
External linksJ. Biol. Chem. / PubMed:15548515
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-1xc9:
Structure of a high-fidelity polymerase bound to a benzo[a]pyrene adduct that blocks replication
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-BAP:
1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE

ChemComp-SO4:
SULFATE ION

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • geobacillus stearothermophilus (bacteria)
KeywordsTRANSFERASE/DNA / DNA polymerase I; DNA replication; klenow fragment; benzo[a]pyrene; benzopyrene; DNA lesion; translation replication / TRANSFERASE-DNA COMPLEX

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