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Structure paper

TitleStructural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 119, Page 481-489, Year 2004
Publish dateOct 30, 2003 (structure data deposition date)
AuthorsWestover, K.D. / Bushnell, D.A. / Kornberg, R.D.
External linksCell(Cambridge,Mass. ) / PubMed:15537538
MethodsX-ray diffraction
Resolution2.3 - 4.25 Å
Structure data

PDB-1r9s:
RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MATCHED NUCLEOTIDE
Method: X-RAY DIFFRACTION / Resolution: 4.25 Å

PDB-1r9t:
RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MISMATCHED NUCLEOTIDE
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

PDB-1twa:
RNA polymerase II complexed with ATP
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-1twc:
RNA polymerase II complexed with GTP
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-1twf:
RNA polymerase II complexed with UTP at 2.3 A resolution
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1twg:
RNA polymerase II complexed with CTP
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

PDB-1twh:
RNA polymerase II complexed with 2'dATP
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-UTP:
URIDINE 5'-TRIPHOSPHATE / UTP*YM

ChemComp-ZN:
Unknown entry

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-MN:
Unknown entry

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

ChemComp-CTP:
CYTIDINE-5'-TRIPHOSPHATE

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsTRANSCRIPTION/DNA-RNA HYBRID / TRANSCRIPTION / MRNA / MULTIPROTEIN COMPLEX / MOLECULAR MACHINE / DNA / TRANSCRIPTION-DNA-RNA COMPLEX / TRANSCRIPTION-DNA-RNA HYBRID complex / ZINC MOTIFS

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