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Structure paper

TitleStructure and Reactivity of Human Mitochondrial 2,4-Dienoyl-Coa Reductase: Enzyme-Ligand Interactions in a Distinctive Short-Chain Reductase Active Site
Journal, issue, pagesJ. Biol. Chem., Vol. 280, Page 3068-, Year 2005
Publish dateAug 24, 2004 (structure data deposition date)
AuthorsAlphey, M.S. / Yu, W. / Byres, E. / Li, D. / Hunter, W.N.
External linksJ. Biol. Chem. / PubMed:15531764
MethodsX-ray diffraction
Resolution1.75 - 2.2 Å
Structure data

PDB-1w6u:
Structure of human DECR ternary complex
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-1w73:
Binary structure of human DECR solved by SeMet SAD.
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-1w8d:
Binary structure of human DECR.
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-HXC:
HEXANOYL-COENZYME A

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / DIENOYL COA-REDUCTASE / SHORT CHAIN DEHYDROGENASE / BETA-OXIDATION / NADP / REDUCTASE / SELENOMETHIONINE / SAD / DIENOYL-COA

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