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Structure paper

TitleEvidence That the Fosfomycin Target Cys115 in UDP-N-acetylglucosamine Enolpyruvyl Transferase (MurA) Is Essential for Product Release.
Journal, issue, pagesJ. Biol. Chem., Vol. 280, Page 3757-3763, Year 2005
Publish dateDec 22, 2003 (structure data deposition date)
AuthorsEschenburg, S. / Priestman, M. / Schonbrunn, E.
External linksJ. Biol. Chem. / PubMed:15531591
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-1ryw:
C115S MurA liganded with reaction products
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-EPU:
URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • enterobacter cloacae (bacteria)
KeywordsTRANSFERASE / inside-out alpha-beta barrel

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