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TitleHuman fatty acid synthase: structure and substrate selectivity of the thioesterase domain.
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 101, Page 15567-15572, Year 2004
Publish dateSep 29, 2004 (structure data deposition date)
AuthorsChakravarty, B. / Gu, Z. / Chirala, S.S. / Wakil, S.J. / Quiocho, F.A.
External linksProc. Natl. Acad. Sci. Usa / PubMed:15507492
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-1xkt:
Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
Keywordshydroxylase / Human fatty acid synthase / thioesterase / specificity / drug target

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