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Structure paper

TitleStructural analysis of autoinhibition in the ras activator son of sevenless.
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 119, Page 393-405, Year 2004
Publish dateSep 3, 2004 (structure data deposition date)
AuthorsSondermann, H. / Soisson, S.M. / Boykevisch, S. / Yang, S.S. / Bar-Sagi, D. / Kuriyan, J.
External linksCell(Cambridge,Mass. ) / PubMed:15507210
MethodsX-ray diffraction
Resolution2.7 - 4.1 Å
Structure data

PDB-1xd2:
Crystal Structure of a ternary Ras:SOS:Ras*GDP complex
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-1xd4:
Crystal structure of the DH-PH-cat module of Son of Sevenless (SOS)
Method: X-RAY DIFFRACTION / Resolution: 3.64 Å

PDB-1xdv:
Experimentally Phased Structure of Human the Son of Sevenless protein at 4.1 Ang.
Method: X-RAY DIFFRACTION / Resolution: 4.1 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Ras:SOS complex / Ras-nucleotide exchange factor complex / nucleotide exchange factor / Ras / Cdc25 / Ras exchanger motif (Rem) / Dbl homology(DH) / pleckstrin homology (PH)

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