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Structure paper

TitleCrystal structure of human factor VIIa/tissue factor in complex with peptide mimetic inhibitor
Journal, issue, pagesBiochem. Biophys. Res. Commun., Vol. 324, Page 1227-1233, Year 2004
Publish dateOct 2, 2004 (structure data deposition date)
AuthorsKadono, S. / Sakamoto, A. / Kikuchi, Y. / Oh-eda, M. / Yabuta, N. / Koga, T. / Hattori, K. / Shiraishi, T. / Haramura, M. / Kodama, H. ...Kadono, S. / Sakamoto, A. / Kikuchi, Y. / Oh-eda, M. / Yabuta, N. / Koga, T. / Hattori, K. / Shiraishi, T. / Haramura, M. / Kodama, H. / Esaki, T. / Sato, H. / Watanabe, Y. / Itoh, S. / Ohta, M. / Kozono, T.
External linksBiochem. Biophys. Res. Commun. / PubMed:15504346
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-1wqv:
Human Factor Viia-Tissue Factor Complexed with propylsulfonamide-D-Thr-Met-p-aminobenzamidine
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-BGC:
beta-D-glucopyranose

ChemComp-FUC:
alpha-L-fucopyranose

ChemComp-CA:
Unknown entry

ChemComp-PSM:
N-[DIHYDROXY(PROPYL)-LAMBDA~4~-SULFANYL]THREONYL-N~1~-{4-[AMINO(IMINO)METHYL]BENZYL}METHIONINAMIDE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / SERINE PROTEASE / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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