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Structure paper

TitleStructure of EthR in a Ligand Bound Conformation Reveals Therapeutic Perspectives against Tuberculosis
Journal, issue, pagesMol. Cell, Vol. 16, Page 301-307, Year 2004
Publish dateAug 10, 2004 (structure data deposition date)
AuthorsFrenois, F. / Engohang-Ndong, J. / Locht, C. / Baulard, A.R. / Villeret, V.
External linksMol. Cell / PubMed:15494316
MethodsX-ray diffraction
Resolution2.3 - 3.3 Å
Structure data

PDB-1u9n:
Crystal structure of the transcriptional regulator EthR in a ligand bound conformation opens therapeutic perspectives against tuberculosis and leprosy
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1u9o:
Crystal structure of the transcriptional regulator EthR in a ligand bound conformation
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

Chemicals

ChemComp-CNS:
HEXADECYL OCTANOATE

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsDNA BINDING PROTEIN / TetR family / transcriptional repressor / protein-ligand complex

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