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-Structure paper
Title | Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP |
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Journal, issue, pages | Biochem. J., Vol. 385, Page 11-20, Year 2005 |
Publish date | Jun 30, 2004 (structure data deposition date) |
Authors | Vucic, D. / Franklin, M.C. / Wallweber, H.J.A. / Das, K. / Eckelman, B.P. / Shin, H. / Elliott, L.O. / Kadkhodayan, S. / Deshayes, K. / Salvesen, G.S. / Fairbrother, W.J. |
External links | Biochem. J. / PubMed:15485396 |
Methods | X-ray diffraction |
Resolution | 1.713 Å |
Structure data | PDB-1tw6: |
Chemicals | ChemComp-ZN: ChemComp-LI: ChemComp-BTB: ChemComp-EDO: ChemComp-HOH: |
Source |
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Keywords | INHIBITOR/APOPTOSIS / ZINC BINDING / PEPTIDE COMPLEX / APOPTOSIS INHIBITION / INHIBITOR-APOPTOSIS COMPLEX |