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-Structure paper
Title | Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 14, Page 5543-5546, Year 2004 |
Publish date | Aug 31, 2004 (structure data deposition date) |
Authors | Zhao, H. / Liu, G. / Xin, Z. / Serby, M.D. / Pei, Z. / Szczepankiewicz, B.G. / Hajduk, P.J. / Abad-Zapatero, C. / Hutchins, C.W. / Lubben, T.H. ...Zhao, H. / Liu, G. / Xin, Z. / Serby, M.D. / Pei, Z. / Szczepankiewicz, B.G. / Hajduk, P.J. / Abad-Zapatero, C. / Hutchins, C.W. / Lubben, T.H. / Ballaron, S.J. / Haasch, D.L. / Kaszubska, W. / Rondinone, C.M. / Trevillyan, J.M. / Jirousek, M.R. |
External links | Bioorg. Med. Chem. Lett. / PubMed:15482920 |
Methods | X-ray diffraction |
Resolution | 2.5 Å |
Structure data | PDB-1xbo: |
Chemicals | ChemComp-IX1: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / Protein Tyrosine Phosphatase 1B / PTP1B / Isoxazole Carboxylic Acid |