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-Structure paper
Title | Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyltransferase inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 14, Page 5367-5370, Year 2004 |
Publish date | Aug 16, 2004 (structure data deposition date) |
![]() | Li, Q. / Claiborne, A. / Li, T. / Hasvold, L. / Stoll, V.S. / Muchmore, S. / Jakob, C.G. / Gu, W. / Cohen, J. / Hutchins, C. ...Li, Q. / Claiborne, A. / Li, T. / Hasvold, L. / Stoll, V.S. / Muchmore, S. / Jakob, C.G. / Gu, W. / Cohen, J. / Hutchins, C. / Frost, D. / Rosenberg, S.H. / Sham, H.L. |
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Methods | X-ray diffraction |
Resolution | 3.5 Å |
Structure data | ![]() PDB-1x81: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-JAN: |
Source |
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![]() | TRANSFERASE / fanesyltransferase |