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Structure paper

TitleChemical Basis for the Affinity Maturation of a Camel Single Domain Antibody
Journal, issue, pagesJ. Biol. Chem., Vol. 279, Page 53593-53601, Year 2004
Publish dateSep 15, 2004 (structure data deposition date)
AuthorsDe Genst, E. / Handelberg, F. / Van Meirhaeghe, A. / Vynck, S. / Loris, R. / Wyns, L. / Muyldermans, S.
External linksJ. Biol. Chem. / PubMed:15383540
MethodsX-ray diffraction
Resolution1.5 Å
Structure data

PDB-1xfp:
Crystal structure of the CDR2 germline reversion mutant of cAb-Lys3 in complex with hen egg white lysozyme
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-FMT:
FORMIC ACID

ChemComp-HOH:
WATER

Source
  • camelus dromedarius (Arabian camel)
  • gallus gallus (chicken)
KeywordsIMMUNE SYSTEM/HYDROLASE / beta sandwich / immunoglobulin fold / protein-protein heterocomplex / alpha-beta othogonal bundle / IMMUNE SYSTEM-HYDROLASE COMPLEX

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