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Structure paper

TitleStructure and mechanistic analysis of the Anti-Human Immunodeficiency Virus Type 1 antibody 2F5 in complex with its gp41 epitope
Journal, issue, pagesJ. Virol., Vol. 78, Page 10724-10737, Year 2004
Publish dateJun 4, 2004 (structure data deposition date)
AuthorsOfek, G. / Tang, M. / Sambor, A. / Katinger, H. / Mascola, J.R. / Wyatt, R. / Kwong, P.D.
External linksJ. Virol. / PubMed:15367639
MethodsX-ray diffraction
Resolution2 - 2.2 Å
Structure data

PDB-1tjg:
Crystal Structure of the broadly neutralizing anti-HIV-1 antibody 2F5 in complex with a gp41 7mer epitope
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1tjh:
Crystal Structure of the broadly neutralizing anti-HIV-1 antibody 2F5 in complex with a gp41 11mer epitope
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-1tji:
Crystal Structure of the broadly neutralizing anti-HIV-1 antibody 2F5 in complex with a gp41 17mer epitope
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-IPA:
ISOPROPYL ALCOHOL / alkaloid*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsViral protein/Immune system / 2F5; ANTIBODY; GP41; HIV-1; NEUTRALIZING; MEMBRANE-PROXIMAL / Viral protein-Immune system COMPLEX / 2F5 / antibody / gp41 / HIV-1 / neutralizing / membrane-proximal

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