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Structure paper

TitleCrystal Structure of T-protein of the Glycine Cleavage System: Cofactor binding, insights into H-protein recognition, and molecular basis for understanding nonketotic hyperglycinemia
Journal, issue, pagesJ. Biol. Chem., Vol. 279, Page 50514-50523, Year 2004
Publish dateAug 24, 2004 (structure data deposition date)
AuthorsLee, H.H. / Kim, D.J. / Ahn, H.J. / Ha, J.Y. / Suh, S.W.
External linksJ. Biol. Chem. / PubMed:15355973
MethodsX-ray diffraction
Resolution1.84 - 2.4 Å
Structure data

PDB-1woo:
Crystal structure of T-protein of the Glycine Cleavage System
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-1wop:
Crystal Structure of T-protein of the Glycine Cleavage System
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1wor:
Crystal Structure of T-protein of the Glycine Cleavage System
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-1wos:
Crystal Structure of T-protein of the Glycine Cleavage System
Method: X-RAY DIFFRACTION / Resolution: 1.84 Å

Chemicals

ChemComp-THG:
(6S)-5,6,7,8-TETRAHYDROFOLATE

ChemComp-HOH:
WATER

ChemComp-FFO:
N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid

ChemComp-RED:
DIHYDROLIPOIC ACID

Source
  • thermotoga maritima (bacteria)
KeywordsTRANSFERASE / Glycine cleavage system / tetrahydrofolate / T-protein / Aminomethyltransferase / folinic acid / dihydrolipoic acid

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