+Search query
-Structure paper
Title | Potent and selective P2-P3 ketoamide inhibitors of cathepsin K with improved pharmacokinetic properties via favorable P1', P1, and/or P3 substitutions |
---|---|
Journal, issue, pages | BIOORG. MED. CHEM. LETT., Vol. 14, Page 4897-4902, Year 2004 |
Publish date | Jun 24, 2004 (structure data deposition date) |
Authors | Barrett, D.G. / Catalano, J.G. / Deaton, D.N. / Hassell, A.M. / Long, S.T. / Miller, A.B. / Miller, L.R. / Shewchuk, L.M. / Wells-Knecht, K.J. / Willard, D.H. / Wright, L.L. |
External links | BIOORG. MED. CHEM. LETT. / PubMed:15341947 |
Methods | X-ray diffraction |
Resolution | 1.75 Å |
Structure data | PDB-1tu6: |
Chemicals | ChemComp-SO4: ChemComp-FSP: ChemComp-HOH: |
Source |
|
Keywords | HYDROLASE / catk / cysteine protease |