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TitleStructural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
Journal, issue, pagesJ. Biol. Chem., Vol. 279, Page 47352-47362, Year 2004
Publish dateJul 3, 2004 (structure data deposition date)
AuthorsKristelly, R. / Gao, G. / Tesmer, J.J.
External linksJ. Biol. Chem. / PubMed:15331592
MethodsX-ray diffraction
Resolution2.13 - 3.22 Å
Structure data

PDB-1txd:
Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF
Method: X-RAY DIFFRACTION / Resolution: 2.13 Å

PDB-1x86:
Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF in complex with RhoA
Method: X-RAY DIFFRACTION / Resolution: 3.22 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / helical bundle (DH) / beta sandwich (PH) / signaling protein/membrane protein / alpha/beta (RhoA) / signaling protein-membrane protein COMPLEX

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