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TitleRational design of RAR-selective ligands revealed by RARbeta crystal structure
Journal, issue, pagesEmbo Rep., Vol. 5, Page 877-882, Year 2004
Publish dateAug 26, 2004 (structure data deposition date)
AuthorsGermain, P. / Kammerer, S. / Perez, E. / Peluso-Iltis, C. / Tortolani, D. / Zusi, F.C. / Starrett, J. / Lapointe, P. / Daris, J.P. / Marinier, A. ...Germain, P. / Kammerer, S. / Perez, E. / Peluso-Iltis, C. / Tortolani, D. / Zusi, F.C. / Starrett, J. / Lapointe, P. / Daris, J.P. / Marinier, A. / De Lera, A.R. / Rochel, N. / Gronemeyer, H.
External linksEmbo Rep. / PubMed:15319780
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-1xap:
Structure of the ligand binding domain of the Retinoic Acid Receptor beta
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-TTB:
4-[(1E)-2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)PROP-1-ENYL]BENZOIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / nuclear receptor / ligand binding domain / retinoic acid receptor beta / TTNPB

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