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TitleBinding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 51, Page 473-489, Year 1995
Publish dateFeb 2, 1995 (structure data deposition date)
AuthorsHiremath, C.N. / Grant, R.A. / Filman, D.J. / Hogle, J.M.
External linksActa Crystallogr. ,Sect. D / PubMed:15299834
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-1piv:
BINDING OF THE ANTIVIRAL DRUG WIN51711 TO THE SABIN STRAIN OF TYPE 3 POLIOVIRUS: STRUCTURAL COMPARISON WITH DRUG BINDING IN RHINOVIRUS 14
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-W71:
5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE

ChemComp-MYR:
MYRISTIC ACID

Source
  • poliovirus type 3 (strains p3/leon/37 and p3/leon 12a[1]b)
KeywordsVIRUS / Icosahedral virus

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