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TitleAnthracycline-DNA interactions at unfavourable base-pair triplet-binding sites: structures of d(CGGCCG)/daunomycin and d(TGGCCA)/adriamycin complexes.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 49, Page 458-467, Year 1993
Publish dateJan 21, 1993 (structure data deposition date)
AuthorsLeonard, G.A. / Hambley, T.W. / McAuley-Hecht, K. / Brown, T. / Hunter, W.N.
External linksActa Crystallogr. ,Sect. D / PubMed:15299505
MethodsX-ray diffraction
Resolution1.7 - 1.9 Å
Structure data

PDB-110d:
ANTHRACYCLINE-DNA INTERACTIONS AT UNFAVOURABLE BASE BASE-PAIR TRIPLET-BINDING SITES: STRUCTURES OF D(CGGCCG)/DAUNOMYCIN AND D(TGGCCA)/ADRIAMYCIN COMPL
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-1da9:
ANTHRACYCLINE-DNA INTERACTIONS AT UNFAVOURABLE BASE BASE-PAIR TRIPLET-BINDING SITES: STRUCTURES OF D(CGGCCG)/DAUNOMYCIN AND D(TGGCCA)/ADRIAMYCIN COMPL
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-DM1:
DAUNOMYCIN / medication, chemotherapy*YM

ChemComp-HOH:
WATER

ChemComp-DM2:
DOXORUBICIN / medication, chemotherapy*YM

KeywordsDNA / RIGHT HANDED DNA / DOUBLE HELIX / COMPLEXED WITH DRUG

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