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TitleStaphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase: crystal structure and mechanism
Journal, issue, pagesJ. Biol. Chem., Vol. 279, Page 44883-44888, Year 2004
Publish dateJun 30, 2004 (structure data deposition date)
AuthorsCampobasso, N. / Patel, M. / Wilding, I.E. / Kallender, H. / Rosenberg, M. / Gwynn, M.
External linksJ. Biol. Chem. / PubMed:15292254
MethodsX-ray diffraction
Resolution2 - 2.501 Å
Structure data

PDB-1tvz:
Crystal structure of 3-hydroxy-3-methylglutaryl-coenzyme A synthase from Staphylococcus aureus
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1txt:
Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase
Method: X-RAY DIFFRACTION / Resolution: 2.501 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-CAA:
ACETOACETYL-COENZYME A

Source
  • staphylococcus aureus (bacteria)
KeywordsLYASE / HMG-CoA synthase; HMGS / coenzyme A; thiolase fold; condensing enzyme; cholesterol biosynthesis

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