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TitleCrystal Structure and Mutagenesis of a Protein Phosphatase-1:Calcineurin Hybrid Elucidate the Role of the {beta}12-{beta}13 Loop in Inhibitor Binding
Journal, issue, pagesJ. Biol. Chem., Vol. 279, Page 43198-43206, Year 2004
Publish dateJul 20, 2004 (structure data deposition date)
AuthorsMaynes, J.T. / Perreault, K.R. / Cherney, M.M. / Luu, H.A. / James, M.N.G. / Holmes, C.F.B.
External linksJ. Biol. Chem. / PubMed:15280359
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1u32:
Crystal structure of a Protein Phosphatase-1: Calcineurin Hybrid Bound to Okadaic Acid
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-OKA:
OKADAIC ACID / toxin*YM

ChemComp-BME:
BETA-MERCAPTOETHANOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE

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