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Structure paper

TitleThe Structure of Human Microsomal Cytochrome P450 3A4 Determined by X-ray Crystallography to 2.05-A Resolution
Journal, issue, pagesJ. Biol. Chem., Vol. 279, Page 38091-38094, Year 2004
Publish dateJun 17, 2004 (structure data deposition date)
AuthorsYano, J.K. / Wester, M.R. / Schoch, G.A. / Griffin, K.J. / Stout, C.D. / Johnson, E.F.
External linksJ. Biol. Chem. / PubMed:15258162
MethodsX-ray diffraction
Resolution2.05 Å
Structure data

PDB-1tqn:
Crystal Structure of Human Microsomal P450 3A4
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / P450 / CYP3A4 / monooxygenase / drug metabolizing enzyme / heme

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