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TitleA new class of peroxisome proliferator-activated receptor agonists with a novel binding epitope shows antidiabetic effects
Journal, issue, pagesJ. Biol. Chem., Vol. 279, Page 41124-41130, Year 2004
Publish dateJul 1, 2004 (structure data deposition date)
AuthorsOstberg, T. / Svensson, S. / Selen, G. / Uppenberg, J. / Thor, M. / Sundbom, M. / Sydow-Backman, M. / Gustavsson, A.L. / Jendeberg, L.
External linksJ. Biol. Chem. / PubMed:15258145
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-1wm0:
PPARgamma in complex with a 2-BABA compound
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-PLB:
2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION/SIGNALING PROTEIN / three-layer helical domain / TRANSCRIPTION-SIGNALING PROTEIN COMPLEX

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