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TitleReplication by human DNA polymerase-iota occurs by Hoogsteen base-pairing.
Journal, issue, pagesNature, Vol. 430, Page 377-380, Year 2004
Publish dateApr 27, 2004 (structure data deposition date)
AuthorsNair, D.T. / Johnson, R.E. / Prakash, S. / Prakash, L. / Aggarwal, A.K.
External linksNature / PubMed:15254543
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-1t3n:
Structure of the catalytic core of DNA polymerase Iota in complex with DNA and dTTP
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-TTP:
THYMIDINE-5'-TRIPHOSPHATE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
Keywordsreplication/DNA / protein / DNA / dTTP / replication-DNA COMPLEX

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