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-Structure paper
Title | The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket |
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Journal, issue, pages | J. Biol. Chem., Vol. 279, Page 39824-39828, Year 2004 |
Publish date | Jun 16, 2004 (structure data deposition date) |
Authors | Pineda, A.O. / Chen, Z.-W. / Caccia, S. / Cantwell, A.M. / Savvides, S.N. / Waksman, G. / Mathews, F.S. / Di Cera, E. |
External links | J. Biol. Chem. / PubMed:15252033 |
Methods | X-ray diffraction |
Resolution | 2.4 - 2.8 Å |
Structure data | PDB-1tq0: PDB-1tq7: |
Chemicals | ChemComp-HOH: ChemComp-ZN: ChemComp-0G6: ChemComp-NAG: |
Source |
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Keywords | BLOOD CLOTTING / thrombin / anticoagulant / HYDROLASE/HYDROLASE INHIBITOR / PPACK / HYDROLASE-HYDROLASE INHIBITOR COMPLEX |