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TitleStructural basis of light chain amyloidogenicity: comparison of the thermodynamic properties, fibrillogenic potential and tertiary structural features of four V(lambda)6 proteins
Journal, issue, pagesJ. Mol. Recog., Vol. 17, Page 323-331, Year 2004
Publish dateMay 22, 2003 (structure data deposition date)
AuthorsWall, J.S. / Gupta, V. / Wilkerson, M. / Schell, M. / Loris, R. / Adams, P. / Solomon, A. / Stevens, F. / Dealwis, C.
External linksJ. Mol. Recog. / PubMed:15227639
MethodsX-ray diffraction
Resolution1.6 - 1.9 Å
Structure data

PDB-1pew:
High Resolution Crystal Structure of Jto2, a mutant of the non-amyloidogenic Lamba6 Light Chain, Jto
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-1pw3:
Crystal structure of JtoR68S
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-CD:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Beta Sheet / Light Chain / amyloidosis

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