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TitleThe structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance.
Journal, issue, pagesJ Immunol., Vol. 173, Page 402-409, Year 2004
Publish dateApr 12, 2004 (structure data deposition date)
AuthorsWebb, A.I. / Borg, N.A. / Dunstone, M.A. / Kjer-Nielsen, L. / Beddoe, T. / McCluskey, J. / Carbone, F.R. / Bottomley, S.P. / Aguilar, M.I. / Purcell, A.W. / Rossjohn, J.
External linksJ Immunol. / PubMed:15210799
MethodsX-ray diffraction
Resolution1.8 - 2 Å
Structure data

PDB-1t0m:
Conformational switch in polymorphic H-2K molecules containing an HSV peptide
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1t0n:
Conformational switch in polymorphic H-2K molecules containing an HSV peptide
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / Immunoglobulin domain / MHC class I alpha domains / HSV peptide

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