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TitleThe Structure of Human Cytochrome P450 2C9 Complexed with Flurbiprofen at 2.0 A Resolution
Journal, issue, pagesJ. Biol. Chem., Vol. 279, Page 35630-35637, Year 2004
Publish dateOct 30, 2003 (structure data deposition date)
AuthorsWester, M.R. / Yano, J.K. / Schoch, G.A. / Yang, C. / Griffin, K.J. / Stout, C.D. / Johnson, E.F.
External linksJ. Biol. Chem. / PubMed:15181000
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1r9o:
Crystal Structure of P4502C9 with Flurbiprofen bound
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-FLP:
FLURBIPROFEN / antiinflammatory*YM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / P450 / monooxygenase / drug metabolizing enzyme / heme

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