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-Structure paper
Title | Mechanisms of camptothecin resistance by human topoisomerase I mutations |
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Journal, issue, pages | J. Mol. Biol., Vol. 339, Page 773-784, Year 2004 |
Publish date | Dec 8, 2003 (structure data deposition date) |
Authors | Chrencik, J.E. / Staker, B.L. / Burgin, A.B. / Pourquier, P. / Pommier, Y. / Stewart, L. / Redinbo, M.R. |
External links | J. Mol. Biol. / PubMed:15165849 |
Methods | X-ray diffraction |
Resolution | 2.3 - 2.6 Å |
Structure data | PDB-1rr8: PDB-1rrj: |
Chemicals | ChemComp-TTG: ChemComp-TTC: ChemComp-HOH: |
Source |
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Keywords | ISOMERASE/DNA / Protein-DNA complex / Topotecan / Camptothecin / Nucleic Acid / Human Topoisomerase I / ISOMERASE-DNA COMPLEX |