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TitleStructure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl)imidazole at 1.9 {angstrom} resolution: Insight into the range of P450 conformations and coordination of redox partner binding.
Journal, issue, pagesJ. Biol. Chem., Vol. 279, Page 27294-27301, Year 2004
Publish dateMar 26, 2004 (structure data deposition date)
AuthorsScott, E.E. / White, M.A. / He, Y.A. / Johnson, E.F. / Stout, C.D. / Halpert, J.R.
External linksJ. Biol. Chem. / PubMed:15100217
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-1suo:
Structure of mammalian cytochrome P450 2B4 with bound 4-(4-chlorophenyl)imidazole
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-CPZ:
4-(4-CHLOROPHENYL)IMIDAZOLE

ChemComp-HOH:
WATER

Source
  • oryctolagus cuniculus (rabbit)
KeywordsOXIDOREDUCTASE / membrane protein / CYP 2B4 / CYP LM2 / Cytochrome p450 / Monooxygenase

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