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TitleFlap Position of Free Memapsin 2 (beta-Secretase), a Model for Flap Opening in Aspartic Protease Catalysis
Journal, issue, pagesBiochemistry, Vol. 43, Page 4689-4695, Year 2004
Publish dateFeb 24, 2004 (structure data deposition date)
AuthorsHong, L. / Tang, J.
External linksBiochemistry / PubMed:15096037
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1sgz:
Crystal Structure of Unbound Beta-Secretase Catalytic Domain.
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / beta-secretase / memapsin / BACE / aspartic protease / protease flap / drug design / Asp2 / Alzheimer's disease

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