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TitleCrystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues
Journal, issue, pagesMol. Endocrinol., Vol. 18, Page 1798-1807, Year 2004
Publish dateSep 13, 2004 (structure data deposition date)
AuthorsQiu, W. / Zhou, M. / Labrie, F. / Lin, S.-X.
External linksMol. Endocrinol. / PubMed:15087468
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1xf0:
Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3) complexed with delta4-androstene-3,17-dione and NADP
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-ASD:
4-ANDROSTENE-3-17-DIONE / hormone*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / alpha/beta barrel / beta-hairpin

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