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TitleStructural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase
Journal, issue, pagesStructure, Vol. 12, Page 429-438, Year 2004
Publish dateNov 19, 2003 (structure data deposition date)
AuthorsKamata, K. / Mitsuya, M. / Nishimura, T. / Eiki, J. / Nagata, Y.
External linksStructure / PubMed:15016359
MethodsX-ray diffraction
Resolution2.3 - 3.4 Å
Structure data

PDB-1v4s:
Crystal structure of human glucokinase
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1v4t:
Crystal structure of human glucokinase
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

Chemicals

ChemComp-GLC:
alpha-D-glucopyranose

ChemComp-NA:
Unknown entry

ChemComp-MRK:
2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / hexokinase IV / allosteric enzyme / diabetes

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